Reperfusion Therapy in Wake-Up Stroke: A Retrospective Observational Study
نویسندگان
چکیده
Abbreviations: ASPECTS: Alberta Stroke Program Early CT Score; CT: Computed Tomography; EIC: Early Ischemic Changes; FKA: First Known Abnormal; IQR: Interquartile Range; IV: Intravenous; LKN: Last Known Normal; mRS: modified Rankin Scale; MRI: Magnetic Resonance Imaging; rtPA: recombinant Tissue plasminogen Activator; SD: Standard Deviation; SICH: Symptomatic Intracerebral Haemorrhage; SITS-MOST: Safe Implementation of Thrombolysis in Stroke Monitoring Study; WUS: Wake-Up Stroke
منابع مشابه
Wake-up Stroke and Onset-to-door Duration Delays: Potential Future Indications for Reperfusion Therapy.
INTRODUCTION There is limited utilisation of acute stroke reperfusion treatments which have narrow therapeutic windows, with delayed hospital presentation being a major limiting factor in Singapore. Most patients who wake up with symptoms are ineligible for reperfusion treatments as duration from onset time is not known. We studied the profile of wake-up strokes, onset-to-door duration and thei...
متن کاملCan We Extend Thrombolytic Treatment for Wake-Up Stroke?
A previous study suggested that WUS onset time is close to wake-up time [2] . For this reason, WUS might respond to thrombolytic therapy. The clinical benefits of acute thrombolytic therapy for IS patients requires the presence of a salvageable penumbra. Considering the estimated previously reported penumbra rates, Koton et al. estimated that 164–328 of 820 WUS patients could be additional pote...
متن کاملCan we extend thrombolytic treatment for wake-up stroke?.
A previous study suggested that WUS onset time is close to wake-up time [2] . For this reason, WUS might respond to thrombolytic therapy. The clinical benefits of acute thrombolytic therapy for IS patients requires the presence of a salvageable penumbra. Considering the estimated previously reported penumbra rates, Koton et al. estimated that 164–328 of 820 WUS patients could be additional pote...
متن کاملReperfusion therapies for wake-up stroke: systematic review.
Reperfusion Therapies for Wake-Up Stroke: Systematic Review Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke published online May 8, 2014; Stroke. http://stroke.ahajournals.org/content/early/2014/05/08/STROKEAHA.114.005126.citation W...
متن کاملWake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome.
BACKGROUND Stroke symptoms noticed upon waking, wake-up stroke, account for up to a quarter of all acute ischemic strokes. Patients with wake-up stroke, however, are often excluded from thrombolytic therapy. METHODS Using our prospectively collected stroke registry, wake-up stroke and known-onset morning strokes were identified. Wakeup stroke was defined as a patient who was asleep >3 hours a...
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